Nephrotic Syndrome

Key points

• Nephrotic syndrome Triad of:
• 1. Proteinuria (> 3g/24hr) causing
• 2. Hypoalbuminaemia (< 30g/L) and
• 3. Oedema Loss of antithrombin-lll, proteins C and S and an associated rise in fibrinogen levels predispose to thrombosis. Loss of thyroxine-binding globulin lowers the total, but not free, thyroxine levels.
• 3. Oedema Loss of antithrombin-lII, proteins C and S and an associated rise in fibrinogen levels predispose to thrombosis. Loss of thyroxine-binding globulin lowers the total, but not free, thyroxine levels.