Chronic Kidney Disease: Bone Disease

Key points

• Chronic kidney disease: bone disease Basic problems in chronic kidney disease
• low vitamin D (1-alpha hydroxylation normally occurs in the kidneys)
• high phosphate
• low calcium: due to lack of vitamin D, high phosphate
• secondary hyperparathyroidism: due to low calcium, high phosphate and low vitamin D Several clinical manifestations may result: Osteitis fibrosa cystica