Hypothalamus

Key points

• 5-HT3 Antagonists (Antiemetics) vs medulla oblongata
• 5-HT3 antagonists are antiemetics used mainly in the management of chemotherapy-related nausea. They mainly act in the chemoreceptor trigger zone area of the medulla oblongata.
• granisetron Adverse effects
• constipation is common
• prolonged QT interval