Neurofibromatosis

Key points

• Neurofibromatosis — NF1: café-au-lait spots, axillary/groin freckling, iris hamartomas (Lisch nodules), neurofibromas, and an association with phaeochromocytoma. NF2: bilateral vestibular (acoustic) neuromas and other CNS tumours.
• Comparison of neurof1bromatosis and tuberous sclerosis. Note
• that whilst they are both autosomal dominant neurocutaneous
• disorders there is little overlap otherwise
• *these of course are more commonly associated with