Post-Lumbar Puncture Headache

Key points

• Post-lumbar puncture headache Headache following lumbar puncture (LP) occurs in approximately one- third of patients. The pathophysiology of is unclear but may relate to a 'leak' of CSF following dural puncture.
• usually develops within 24-48 hours following LP but may occur up to one week later
• may last several days
• worsens with upright position
• improves with recumbent position