Sulfasalazine

Key points

• Sulfasalazine is a disease modifying anti-rheumatic drug used in the management of inflammatory arthritis, especially rheumatoid arthritis; also used in inflammatory bowel disease
• Caution: G6PD deficiency
• Caution: allergy to aspirin or sulphonamides (cross-sensitivity)
• Adverse effects: Stevens-Johnson syndrome
• Adverse effects: pneumonitis / lung fibrosis