Systemic Lupus Erythematosus: Features

Key points

• Systemic lupus erythematosus (SLE) is a multisystem, autoimmune disorder. It typically presents in early adulthood and is more common in women and people of Afro-Caribbean origin. General features
• lymphadenopathy Skin
• malar (butterfly) rash: spares nasolabial folds
• discoid rash: scaly, erythematous, well demarcated rash in sun-exposed areas. Lesions may progress to become pigmented and hyperkeratotic before becoming atrophic
• photosensitivity