Motion Sickness

Key points

• Motion sickness: nausea/vomiting from visual-vestibular sensory mismatch.
• BNF: hyoscine (e.g. transdermal patch) is the most effective treatment — use limited by side effects.
• Non-sedating antihistamines (cyclizine, cinnarizine) preferred over sedating ones (promethazine).
• Hierarchy: hyoscine > cyclizine/cinnarizine > promethazine.