Botulinum Toxin (Botox)

Key points

• Licensed uses beyond cosmetics: blepharospasm · hemifacial spasm · focal spasticity (including post-stroke hand/wrist disability, cerebral palsy) · spasmodic torticollis · severe axillary hyperhidrosis · achalasia.
• Acts by inhibiting acetylcholine release at the neuromuscular junction.