Pharmacology · Pathway 13
Corticosteroids: Side Effects
Key points
- Glucocorticoid side effects: weight gain, easy bruising, osteoporosis, diabetes, hypertension, proximal myopathy, thin skin, cataracts, glaucoma, psychosis, adrenal suppression.
- Mineralocorticoid effects: fluid retention, hypertension, hypokalaemia.
- Immunosuppression: increased infection risk (including TB reactivation and atypical infections).
- Never stop long-term steroids abruptly — risk of Addisonian crisis; taper gradually.
- Patients on >3 weeks of steroids or repeated courses should carry a steroid card.
Decision points in this pathway
- Long-term steroid to stop?
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