Infectious Diseases · Pathway 46

Non-Gonococcal Urethritis

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Key points

Non-gonococcal urethritis (NGU, sometimes referred to as non-specific urethritis) is a term used to describe the presence of urethritis when a gonococcal bacteria are not identifiable or the initial swab.
Chlamydia trachomatis - most common cause
Mycoplasma genitalium - thought to cause more symptoms than Chlamydia Management
contact tracing
TREATMENT: DOXYCYCLINE 100 mg twice daily for 7 days is now the preferred first-line option, with azithromycin an ALTERNATIVE — BASHH moved away from single-dose azithromycin because of increasing MACROLIDE RESISTANCE in Mycoplasma genitalium, which single-dose azithromycin can induce.
Where Mycoplasma genitalium is identified or suspected, test for macrolide resistance and treat under specialist guidance — do NOT simply give repeated single-dose azithromycin.