Haematology-Oncology · Pathway 63
Superior Vena Cava Obstruction
Key points
- Oncological emergency; most commonly lung cancer (NSCLC, lymphoma; also metastatic seminoma, Kaposi's, breast).
- Features: dyspnoea (commonest) · face/neck/arm swelling · morning headache · visual disturbance · pulseless JVD.
- Non-malignant: aortic aneurysm · mediastinal fibrosis · goitre · SVC thrombosis.
- General: dexamethasone, balloon venoplasty, stenting.
- Small cell → chemotherapy + radiotherapy; non-small cell → radiotherapy.
Decision points in this pathway
- Tumour type?
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