Blood Product Transfusion Complications

Key points

• Blood product transfusion complications may be broadly classified into the following:
• immunological: acute haemolytic, non-haemolytic febrile, allergic/anaphylaxis
• transfusion-related acute lung injury (TRALI)
• fluid overload
• other: hyperkalaemia, iron overload, clotting Acute haemolytic transfusion reaction Acute haemolytic transfusion reaction results from a mismatch of blood group (ABO) which causes massive intravascular haemolysis.