Hodgkin's Lymphoma: Histological Classification and Prognosis

Key points

• Hodgkin's lymphoma is a malignant proliferation of lymphocytes characterised by the presence of the Reed- Sternberg cell.
• weight loss > 10% in last 6 months
• night sweats Other factors associated with a poor prognosis identified in a 1998 NEJM paper included:
• age > 45 years
• stage IV disease