Pregnancy: Jaundice

Key points

• Intrahepatic cholestasis of pregnancy Intrahepatic cholestasis of pregnancy (also known as obstetric cholestasis) occurs in around 1% of pregnancies and is generally seen in the third trimester.
• pruritus, often in the palms and soles
• no rash (although skin changes may be seen due to scratching)
• raised bilirubin Management
• ursodeoxycholic acid is used for symptomatic relief