Inflammatory Bowel Disease: Key Differences

Key points

• The two main types of inflammatory bowel disease are Crohn's disease and Ulcerative colitis. They have many similarities in terms of presenting symptoms, investigation findings and management options.
• increased goblet cells
• granulomas No inflammation beyond submucosa(unless fulminant disease) - inflammatory cell infiltrate in lamina propria
• neutrophils migrate through the walls of glands to form crypt abscesses
• depletion of goblet cells and mucin from gland epithelium