Zollinger-Ellison Syndrome

Key points

• Zollinger-Ellison syndrome is condition characterised by excessive levels of gastrin, usually from a gastrin secreting tumour usually of the duodenum or pancreas. Around 30% occur as part of MEN type I syndrome Features
• multiple gastroduodenal ulcers
• malabsorption Diagnosis
• fasting gastrin levels: the single best screen test
• secretin stimulation test