Helicobacter Pylori

Key points

• Helicobacter pylori is a Gram negative bacteria associated with a variety of gastrointestinal problems, principally peptic ulcer disease Associations
• peptic ulcer disease (95% of duodenal ulcers, 75% of gastric ulcers)
• gastric cancer
• B cell lymphoma of MALT tissue (eradication of H pylori results causes regression in 80% of patients)
• atrophic gastritis The role of H pylori in Gastro-oesophageal reflux disease (GORD) is unclear - there is currently no role in GORD for the eradication of H pylori Management - eradication may be achieved with a 7 day course of