Gastroenterology · Pathway 109
Complications Following Renal Transplant
Key points
- Renal transplantation is widely practised. The commonest technical related complications are related to the ureteric anastomosis.
- Hyperacute. This occurs immediately through presence of pre formed antibody (such as ABO incompatibility).
- Acute. Occurs during the first 6 months and is usually T cell mediated. Usually tissue infiltrates and vascular lesions.
- Chronic. Occurs after the first 6 months. Vascular changes predominate. Hyperacute Renal transplants are most susceptible to this process. Risk factors include major HLA mismatch and ABO incompatibility.