Endocrinology · Pathway 4

Insulinoma

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Key points

Insulinoma An insulinoma is a neuroendocrine tumour deriving mainly from pancreatic Islets of Langerhans cells Basics
most common pancreatic endocrine tumour
10% malignant, 10% multiple
of patients with multiple tumours, 50% have MEN-1 Features
of hypoglycaemia: typically early in morning or just before meal, e.g. diplopia, weakness etc