Dermatology · Pathway 17
Vitiligo & Alopecia
Key points
- Vitiligo: autoimmune depigmentation (well-demarcated white patches); associations — thyroid disease, type 1 diabetes, Addison's, pernicious anaemia (autoimmune cluster).
- Wood's lamp accentuates vitiligo; management — potent topical steroids/tacrolimus, phototherapy, camouflage.
- Alopecia areata: well-demarcated non-scarring patches of hair loss; 'exclamation mark' hairs at the edge.
- Alopecia areata associations: atopy, autoimmune disease, Down's syndrome.
- Scarring alopecias (discoid lupus, lichen planopilaris) destroy follicles — biopsy early.
Decision points in this pathway
- Scarring features (loss of follicular openings)?
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