Mitral Valve Prolapse

Key points

• MVP is common (5–10% of population); usually idiopathic.
• Associations: PDA, ASD · cardiomyopathy · Turner's · Marfan's · Fragile X · osteogenesis imperfecta · pseudoxanthoma elasticum · WPW · long-QT · Ehlers-Danlos · polycystic kidney disease. (Acromegaly is NOT a common association.)
• Features: atypical chest pain or palpitations; mid-systolic click (later with squatting) + late systolic murmur (longer when standing).
• Complications: mitral regurgitation · arrhythmias (including long QT) · emboli · sudden death.